Work Beadle Center (BEAD) N133
Lincoln NE 68588-0664
Work 402-472-7468 On-campus 2-7468
My research program is focused on the biology and biochemistry of the Stabilin receptors and how they affect human physiology and disease. Due to their expression in liver and other tissues of the body, their contribution to extracellular matrix management and the catabolism of certain therapeutic drugs is significant in terms of metabolic half-life.


  • BS, Brigham Young University, 1996
  • Ph D, Louisiana State University Health Sciences Center, 2001


  • BIOC 435, Advanced Topics in Biochemistry; Glycobiology, Fall 2016
  • BIOC 431, Structure and Metabolism, Fall 2017
  • BIOC 831, Structure and Metabolism, Fall 2017

icon-documentPublications and Other Intellectual Contributions

  • Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified Antisense Oligonucleotides (ASOs), Nucleic Acids Research, April (2nd Quarter/Spring) 2016
  • Probing Structural Selectivity of Synthetic Heparin Binding to Stabilin Protein Receptors , Journal of Biological Chemistry, April (2nd Quarter/Spring) 2012
  • In vivo liver endocytosis followed by purification of liver cells by liver perfusion., Journal of visualized experiments : JoVE, November 2011
  • Homogenous and Low-molecular weight heparins, Nature Chemical Biology, February 2014

icon-business-chartResearch & Grants

  • LMWH Clearance, DHHS-NHLBI, March 2016
  • CIBC COBRE, DHHS-Nat Inst Gen Medical Sci, August 2016
  • Synthetic HS, Univ of North Carolina, June 2016


  • Systemic clearance: Natural and synthetic glycosaminoglycan-based drugs cleared by the Stabilin family of receptors., CARB division, San Francisco, CA
  • Heparin containing 3-O sulfation is Required for Hepatic Accumulation, International Society for Hepatic Sinusoidal Research, Asilomar, CA

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